Free Module 3 · Urinary tract infections Integrative case

Fever and flank pain

Level: Medical students · Goal: recognize a systemic urinary tract infection, order the appropriate tests, and identify when it is a urological emergency.

1
Medical history
2
Initial tests
3
Diagnosis
4
Management and drainage
5
Outcome
6
Wrap-up

Emergency department

A 46-year-old woman with no relevant history presents to the emergency department with severe right flank pain of 12 hours' duration. She also reports chills, nausea, and feeling feverish.

On examination:

  • Temperature: 39.1 °C
  • HR: 112 bpm
  • BP: 105/65 mmHg
  • Right lumbar tenderness on palpation.
  • Positive right costovertebral angle percussion.

What tests would you order?

An important detail emerges

The patient now reports that the pain began suddenly, was initially very intense and colicky, and radiated to the right groin.

Imaging

A non-contrast CT is performed.

Report

8 mm stone in the proximal right ureter, with associated pelvicalyceal and proximal ureteral dilation.

What do we do?

The patient remains febrile and tachycardic.

How do we drain it?

Outcome

A double-J stent is placed and empirical intravenous antibiotic treatment is started.

At 48 hours

General conditionAfebrile patient, improved general condition
HR78 bpm
Renal functionImproving

Urine culture

Escherichia coli, with antibiogram available.

What about the stone?

The patient improves and the infection is controlled.

Final challenge

What the student should take away from the case

Core concept

Pyelonephritis + obstruction = urological emergency.

Fever + flank pain
↓
Think of a systemic urinary tract infection
↓
Could there be an obstruction?
↓
Stone disease + hydronephrosis
↓
Infection + obstructed urinary tract
↓
ANTIBIOTICS + SUPPORT + URGENT DRAINAGE
↓
Infection control
↓
Definitive treatment of the stone, afterward
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