A urinary tract infection is the invasion of the urinary tract by microorganisms capable of producing an inflammatory response and symptoms.
It is currently useful to distinguish between:
The patient usually presents with:
When to suspect systemic infection
The presence of fever, chills, flank pain, or deterioration of general condition should make you think of a systemic infection, not simple cystitis.
Escherichia coli is the main uropathogen. Other Enterobacterales and different microorganisms may also be found depending on patient characteristics.
Fundamental concept
Bacteriuria ≠ urinary tract infection. To speak of infection we must interpret symptoms + clinical context + microbiological studies together when they are indicated. Asymptomatic bacteriuria generally represents colonization and should not be treated routinely.
To remember
Dysuria + urinary frequency + urgency without fever → think of cystitis first.
Fever + chills + flank pain → think of systemic infection.
Urinary tract infections — Guide for Medicine: uncomplicated and complicated UTI, pyelonephritis, prostatitis, epididymitis/orchitis, urethritis and STIs, urine culture interpretation, and rational antibiotic use (all 8 topics of the module in a single document).
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