Free Module 7 · Andrology

Male infertility

1

Introduction

Learning objectives
  • Recognize the pretesticular, testicular, and post-testicular causes of male infertility.
  • Know the components of the initial evaluation, including semen analysis.
  • Understand why exogenous testosterone is contraindicated in young men seeking fertility.
2

Video lesson

▶
Video pending upload (embedded YouTube)
3

Summary

What is infertility?

Infertility is considered when a couple fails to achieve pregnancy after an adequate period of regular sexual intercourse without contraception, usually 12 months.

The evaluation should consider both partners.

Why can male infertility occur?

Causes can be conceptually divided into:

Pretesticular

Hormonal abnormalities that affect stimulation of the testis.

Testicular

Impaired sperm production.

Post-testicular

Obstructions or abnormalities that prevent adequate sperm transport.

The following may also play a role:

  • varicocele;
  • genetic abnormalities;
  • infections;
  • cryptorchidism;
  • medications;
  • oncologic treatments;
  • environmental factors and habits.

Initial evaluation

It should include a focused medical history:

  • duration of infertility;
  • previous pregnancies;
  • pubertal development;
  • cryptorchidism;
  • infections;
  • trauma;
  • surgeries;
  • medications;
  • exposure to toxins;
  • sexual function.

Semen analysis

It is one of the fundamental studies.

It evaluates different characteristics of the semen, including:

  • volume;
  • sperm concentration;
  • total count;
  • motility;
  • morphology.

An abnormal result must be interpreted in the clinical context and may require confirmation.

Physical examination

Special attention should be paid to:

  • sexual development;
  • testicular size and consistency;
  • epididymis;
  • vas deferens;
  • presence of varicocele.

Additional studies

Depending on the findings, the following may be requested:

  • hormonal evaluation;
  • ultrasound;
  • genetic studies;
  • other specific investigations.

⚠️ Alert

Administration of exogenous testosterone can reduce or suppress spermatogenesis. This is especially important in young men who wish to preserve fertility.

Key concept

Male infertility does not necessarily mean sterility. The goal is to identify potentially correctable causes and determine the best reproductive strategy for the couple.

4

PDF

⬇ Download lesson summary

Downloadable PDF pending upload.

5

Practical algorithm

  1. Problems achieving or maintaining an erection → erectile dysfunction.
  2. Persistently too-rapid ejaculation + difficulty controlling it + negative impact → premature ejaculation.
  3. Couple unable to conceive → evaluate both partners; in the man, start with history, examination, and semen analysis.
  4. Scrotal venous dilation, predominantly on the left → consider varicocele.
  5. Compatible symptoms + repeatedly low testosterone → evaluate for possible hypogonadism.
  6. Acquired penile curvature + plaque → consider Peyronie's disease.

Andrology does not study sexual function alone. It integrates erectile and ejaculatory function, reproduction, hormonal function, and diseases of the male genital tract.

6

Clinical case

Content pending upload Progressive clinical case focused on decision-making.
7

Self-assessment

Questions pending upload 5–10 multiple-choice questions on this lesson.
8

References

Links pending upload References to PubMed, DOI, scientific society guidelines and journals.

Want us to let you know when this lesson is complete?

All set, we'll let you know! 🎉
← Back to program Next lesson: order to be determined